- 产品信息
商品描述
靶点-Target
PDLI3
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
40kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PDLI3 AA range: 251-301
特异性
This antibody detects endogenous levels of PDLI3 at Human/Mouse/Rat
基因名称
PDLIM3 ALP
蛋白名称
PDLI3
Organism-1
Human
基因ID-1
27295
SwissProt-1
Q53GG5
Organism-2
Mouse
基因ID-2
53318
SwissProt-2
O70209
Organism-3
Rat
基因ID-3
114108
SwissProt-3
Q66HS7
背景
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012],
细胞定位
Cytoplasm, myofibril, sarcomere, Z line . Localizes to myofiber Z-lines.





