- 产品信息
商品描述
靶点-Target
GATM
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
47kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human GATM AA range: 223-273
特异性
This antibody detects endogenous levels of GATM at Human/Mouse/Rat
基因名称
GATM AGAT
蛋白名称
GATM
Organism-1
Human
基因ID-1
2628
SwissProt-1
P50440
Organism-2
Mouse
基因ID-2
67092
SwissProt-2
Q9D964
Organism-3
Rat
基因ID-3
81660
SwissProt-3
P50442
背景
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq, Jul 2008],
细胞定位
[Isoform 1]: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Probably attached to the outer side of the inner membrane.; [Isoform 2]: Cytoplasm.





