FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
C8AP2
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
218kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human C8AP2 AA range: 1155-1205
特异性
This antibody detects endogenous levels of C8AP2 at Human/Mouse
基因名称
CASP8AP2 FLASH KIAA1315 RIP25
蛋白名称
C8AP2
Organism-1
Human
基因ID-1
9994
SwissProt-1
Q9UKL3
Organism-2
Mouse
基因ID-2
26885
SwissProt-2
Q9WUF3
背景
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008],
细胞定位
Cytoplasm. Nucleus. Nucleus, PML body. Mitochondrion. Exported from the nucleus to the mitochondria upon FAS activation.
