FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
OSBL8
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
98kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human OSBL8 AA range: 290-340
特异性
This antibody detects endogenous levels of OSBL8 at Human
基因名称
OSBPL8 KIAA1451 ORP8 OSBP10
蛋白名称
OSBL8
Organism-1
Human
基因ID-1
114882
SwissProt-1
Q9BZF1
背景
This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
细胞定位
[Isoform 1]: Endoplasmic reticulum membrane ; Single-pass membrane protein . Nucleus membrane . The presence of the N-terminus extension contains an overall negative charge that may explain the weak localization to the cortical endoplasmic reticulum (Probable). .; [Isoform 3]: Endoplasmic reticulum membrane ; Single-pass membrane protein. Localizes to the cortical endoplasmic reticulum at the endoplasmic reticulum-plasma membrane contact sites. .
