DTNA rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617978

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商品描述
  • 靶点-Target

    DTNA

  • 反应性

    Human,Mouse

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    82kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human DTNA AA range: 131-181

  • 特异性

    This antibody detects endogenous levels of DTNA at Human/Mouse

  • 基因名称

    DTNA DRP3

  • 蛋白名称

    DTNA

  • Organism-1

    Human

  • 基因ID-1

    1837

  • SwissProt-1

    Q9Y4J8

  • Organism-2

    Mouse

  • 基因ID-2

    13527

  • SwissProt-2

    Q9D2N4

  • 背景

    The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasm. Cell junction, synapse. Cell membrane . In peripheral nerves, colocalizes with MAGEE1 in the Schwann cell membrane. .