- 产品信息
商品描述
靶点-Target
DTNA
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
82kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DTNA AA range: 131-181
特异性
This antibody detects endogenous levels of DTNA at Human/Mouse
基因名称
DTNA DRP3
蛋白名称
DTNA
Organism-1
Human
基因ID-1
1837
SwissProt-1
Q9Y4J8
Organism-2
Mouse
基因ID-2
13527
SwissProt-2
Q9D2N4
背景
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Cell junction, synapse. Cell membrane . In peripheral nerves, colocalizes with MAGEE1 in the Schwann cell membrane. .





