- 产品信息
商品描述
靶点-Target
FBX46
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
66kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FBX46 AA range: 67-117
特异性
This antibody detects endogenous levels of FBX46 at Human/Mouse/Rat
基因名称
FBXO46 FBX46 FBXO34L
蛋白名称
FBX46
Organism-1
Human
基因ID-1
23403
SwissProt-1
Q6PJ61
Organism-2
Mouse
基因ID-2
243867
SwissProt-2
Q8BG80
Organism-3
Rat
基因ID-3
292686
SwissProt-3
Q4KLY2
背景
Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008],





