Glutaredoxin-1 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617904
- 产品信息
商品描述
靶点-Target
Glutaredoxin-1
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
12kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Glutaredoxin-1 AA range: 8-58
特异性
This antibody detects endogenous levels of human Glutaredoxin-1
基因名称
GLRX GRX
蛋白名称
Glutaredoxin-1
别名
Glutaredoxin-1;Thioltransferase-1;TTase-1;
Organism-1
Human
基因ID-1
2745
SwissProt-1
P35754
背景
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011],
细胞定位
Cytoplasm.





