Serine/threonine-protein kinase BGLF4 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617856
- 产品信息
商品描述
靶点-Target
Serine/threonine-protein kinase BGLF4
反应性
Human virus
应用
ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
推荐稀释比
ELISA(peptide) 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Serine/threonine-protein kinase BGLF4
特异性
This antibody detects endogenous levels of human Serine/threonine-protein kinase BGLF4
基因名称
BGLF4
蛋白名称
Serine/threonine-protein kinase BGLF4
Organism-1
Human
SwissProt-1
P13288
背景
P13288 BGLF4 protein(BGLF4) Human herpesvirus 4 catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Plays many key roles by phosphorylating several proteins including the viral DNA processivity factor BMRF1, EBNA1 or EBNA2. Required for efficient lytic DNA replication and release of nucleocapsids from the nucleus. Contributes to the compaction of host cell chromatin in cells undergoing lytic replication, presumably by phosphorylating the host condensin complex and host TOP2A. Induces disassembly of the nuclear lamina by phosphorylating with host LMNA. Phosphorylates substrates involved in capsid assembly and DNA packaging. Facilitates the switch from latent to lytic DNA replication by down-regulating EBNA1 replication function. Phosphorylates the viral immediate-early protein BZLF1.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:the protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs.,





