NF-E4 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617832

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商品描述
  • 靶点-Target

    NF-E4

  • 反应性

    Human

  • 应用

    IHC,IF,WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    19kD

  • 推荐稀释比

    IHC 1:50-200;WB 1:500-2000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human NF-E4

  • 特异性

    This antibody detects endogenous levels of human NF-E4

  • 基因名称

    NFE4

  • 蛋白名称

    NF-E4

  • 别名

    Transcription factor NF-E4

  • Organism-1

    Human

  • 基因ID-1

    58160

  • SwissProt-1

    Q86UQ8

  • 背景

    The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus .