AGTR1 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617798

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商品描述
  • 靶点-Target

    AGTR1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    41kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:10000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human AGTR1 Polyclonal

  • 特异性

    This antibody detects endogenous levels of AGTR1.

  • 基因名称

    AGTR1 AGTR1A AGTR1B AT2R1 AT2R1B

  • 蛋白名称

    Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1)

  • 别名

    Type-1 angiotensin II receptor;AT1AR;AT1BR;Angiotensin II type-1 receptor;AT1;

  • Organism-1

    Human

  • 基因ID-1

    185

  • SwissProt-1

    P30556

  • 背景

    Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein .