Tyrosine Hydroxylase Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617763
- 产品信息
商品描述
靶点-Target
Tyrosine Hydroxylase
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000;ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Tyrosine Hydroxylase Polyclonal
特异性
This antibody detects endogenous levels of Tyrosine Hydroxylase.
基因名称
TH TYH
蛋白名称
Tyrosine 3-monooxygenase (Tyrosine 3-hydroxylase) (TH),Tyrosine Hydrolase
别名
Tyrosine 3-monooxygenase;Tyrosine 3-hydroxylase;TH;
Organism-1
Human
基因ID-1
7054
SwissProt-1
P07101
Organism-2
Mouse
基因ID-2
21823
SwissProt-2
P24529
Organism-3
Rat
基因ID-3
25085
SwissProt-3
P04177
背景
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, perinuclear region . Nucleus . Cell projection, axon . Cytoplasm . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . When phosphorylated at Ser-19 shows a nuclear distribution and when phosphorylated at Ser-31 as well at Ser-40 shows a cytosolic distribution (By similarity). Expressed in dopaminergic axons and axon terminals. .





