- 产品信息
商品描述
靶点-Target
GCK/GLK
反应性
Human,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
100kD
推荐稀释比
WB 1:500-2000;ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human GCK/GLK. at AA range: 221-270
特异性
GCK/GLK Polyclonal Antibody detects endogenous levels of GCK/GLK
基因名称
MAP4K2/MAP4K3
蛋白名称
GCK/GLK
别名
Mitogen-activated protein kinase kinase kinase kinase 2;B lymphocyte serine/threonine-protein kinase;Germinal center kinase;GC kinase;MAPK/ERK kinase kinase kinase 2;MEK kinase kinase 2;MEKKK 2;Rab8-interacting protein;Mitogen-activated protein kinase kinase kinase kinase 3;Germinal center kinase-related protein kinase;GLK;MAPK/ERK kinase kinase kinase 3;MEK kinase kinase 3;MEKKK 3;
Organism-1
Human
基因ID-1
5871;8491
SwissProt-1
Q12851;Q8IVH8
背景
mitogen-activated protein kinase kinase kinase kinase 2(MAP4K2) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
细胞定位
Cytoplasm . Basolateral cell membrane ; Peripheral membrane protein . Golgi apparatus membrane ; Peripheral membrane protein .





