Integrin β7 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617745

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商品描述
  • 靶点-Target

    Integrin β7

  • 反应性

    Human,Mouse

  • 应用

    WB,ELISA,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    130kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human Integrin β7. at AA range: 671-720

  • 特异性

    Integrin β7 Polyclonal Antibody detects endogenous levels of Integrin β7

  • 基因名称

    ITGB7

  • 蛋白名称

    Integrin β7

  • 别名

    Integrin beta-7;Gut homing receptor beta subunit;

  • Organism-1

    Human

  • 基因ID-1

    3695

  • SwissProt-1

    P26010

  • Organism-2

    Mouse

  • 基因ID-2

    16421

  • SwissProt-2

    P26011

  • 背景

    This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013],

  • 细胞定位

    Membrane; Single-pass type I membrane protein.