LIM and SH3 domain protein 1 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617740

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商品描述
  • 靶点-Target

    LIM and SH3 domain protein 1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    38kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human LIM and SH3 domain protein 1. at AA range: 90-130

  • 特异性

    This antibody detects endogenous levels of LIM and SH3 domain protein 1

  • 基因名称

    LASP1 MLN50

  • 蛋白名称

    LIM and SH3 domain protein 1

  • 别名

    LIM and SH3 domain protein 1;LASP-1;Metastatic lymph node gene 50 protein;MLN 50;

  • Organism-1

    Human

  • 基因ID-1

    3927

  • SwissProt-1

    Q14847

  • Organism-2

    Mouse

  • 基因ID-2

    16796

  • SwissProt-2

    Q61792

  • 背景

    This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012],

  • 细胞定位

    Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Associated with the F-actin rich cortical cytoskeleton. .