FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FIG4
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
110kD
推荐稀释比
WB 1:500-2000;ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FIG4. at AA range: 341-390
特异性
This antibody detects endogenous levels of FIG4
基因名称
FIG4 KIAA0274 SAC3
蛋白名称
FIG4
别名
Polyphosphoinositide phosphatase;Phosphatidylinositol 3,5-bisphosphate 5-phosphatase;SAC domain-containing protein 3;
Organism-1
Human
基因ID-1
9896
SwissProt-1
Q92562
Organism-2
Mouse
基因ID-2
103199
SwissProt-2
Q91WF7
背景
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008],
细胞定位
Endosome membrane . Localization requires VAC14 and PIKFYVE. .
