FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GRB7
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
推荐稀释比
IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic peptide from human protein at AA range: 30-100
特异性
The antibody detects endogenous GRB7
基因名称
GRB7
蛋白名称
Growth factor receptor-bound protein 7 (B47) (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)
别名
Growth factor receptor-bound protein 7;B47;Epidermal growth factor receptor GRB-7;GRB7 adapter protein;
Organism-1
Human
基因ID-1
2886
SwissProt-1
Q14451
Organism-2
Mouse
基因ID-2
14786
SwissProt-2
Q03160
背景
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011],
细胞定位
Cytoplasm . Cell junction, focal adhesion . Cell membrane; Peripheral membrane protein; Cytoplasmic side . Cytoplasmic granule . Cell projection . Predominantly cytoplasmic. Detected in stress granules, where mRNA is stored under stress conditions. .
