FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LT-β
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
25kD
推荐稀释比
IHC 1:50-200;ELISA 1:10000-20000;WB 1:500-2000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic peptide from human protein at AA range: 41-90
特异性
The antibody detects endogenous LT-β
基因名称
LTB TNFC TNFSF3
蛋白名称
Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3)
别名
Lymphotoxin-beta;LT-beta;Tumor necrosis factor C;TNF-C;Tumor necrosis factor ligand superfamily member 3;
Organism-1
Human
基因ID-1
4050
SwissProt-1
Q06643
Organism-2
Mouse
基因ID-2
16994
SwissProt-2
P41155
背景
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Membrane ; Single-pass type II membrane protein .
