- 产品信息
商品描述
靶点-Target
ASCL1
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
推荐稀释比
IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic peptide from human protein at AA range: 190-236
特异性
The antibody detects endogenous ASCL1
基因名称
ASCL1 ASH1 BHLHA46 HASH1
蛋白名称
Achaete-scute homolog 1 (ASH-1) (hASH1) (Class A basic helix-loop-helix protein 46) (bHLHa46)
别名
Achaete-scute homolog 1;ASH-1;hASH1;Class A basic helix-loop-helix protein 46;bHLHa46;
Organism-1
Human
基因ID-1
429
SwissProt-1
P50553
Organism-2
Mouse
基因ID-2
17172
SwissProt-2
Q02067
Organism-3
Rat
SwissProt-3
P19359
背景
achaete-scute family bHLH transcription factor 1(ASCL1) Homo sapiens This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .





