- 产品信息
商品描述
靶点-Target
IL-19
反应性
Human,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
20kD
推荐稀释比
WB 1:500-2000;IHC 1:500-200;ELISA 1:10000-20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic peptide from human protein at AA range: 51-100
特异性
The antibody detects endogenous IL-19
基因名称
IL19 ZMDA1
蛋白名称
Interleukin-19 (IL-19) (Melanoma differentiation-associated protein-like protein) (NG.1)
别名
Interleukin-19;IL-19;Melanoma differentiation-associated protein-like protein;NG.1;
Organism-1
Human
基因ID-1
29949
SwissProt-1
Q9UHD0
Organism-2
Mouse
基因ID-2
329244
SwissProt-2
Q8CJ70
背景
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Secreted.





