DC-LAMP Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617587

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商品描述
  • 靶点-Target

    DC-LAMP

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    44kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:500-200;ELISA 1:10000-20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthetic peptide from human protein at AA range: 261-310

  • 特异性

    The antibody detects endogenous DC-LAMP

  • 基因名称

    LAMP3 DCLAMP TSC403

  • 蛋白名称

    Lysosome-associated membrane glycoprotein 3 (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD antigen CD208)

  • 别名

    Lysosome-associated membrane glycoprotein 3;LAMP-3;Lysosomal-associated membrane protein 3;DC-lysosome-associated membrane glycoprotein;DC LAMP;Protein TSC403;CD antigen CD208;

  • Organism-1

    Human

  • 基因ID-1

    27074

  • SwissProt-1

    Q9UQV4

  • Organism-2

    Mouse

  • 基因ID-2

    239739

  • SwissProt-2

    Q7TST5

  • 背景

    Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010],

  • 细胞定位

    Cell surface . Lysosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle membrane ; Single-pass type I membrane protein . Early endosome membrane ; Single-pass type I membrane protein . During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3 (PubMed:9768752). Detected on lysosomes in mature dendritic cells (PubMed:9768752). .