FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RANK
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
66kD
推荐稀释比
WB 1:500-2000;IHC 1:500-200;ELISA 1:10000-20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic peptide from human protein at AA range: 60-120
特异性
The antibody detects endogenous RANK
基因名称
TNFRSF11A RANK
蛋白名称
Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265)
别名
Tumor necrosis factor receptor superfamily member 11A;Osteoclast differentiation factor receptor;ODFR;Receptor activator of NF-KB;CD antigen CD265;
Organism-1
Human
基因ID-1
8792
SwissProt-1
Q9Y6Q6
Organism-2
Mouse
基因ID-2
21934
SwissProt-2
O35305
背景
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012],
细胞定位
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform RANK-e5a]: Cell membrane ; Single-pass type I membrane protein .
