FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EGF
反应性
Human,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
WB 1:500-2000;IHC 1:500-200;ELISA 1:10000-20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic peptide from human protein at AA range: 1000-1060
特异性
The antibody detects endogenous EGF
基因名称
EGF
蛋白名称
Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)]
别名
Pro-epidermal growth factor;EGF;[Cleaved into: Epidermal growth factor;Urogastrone;]
Organism-1
Human
基因ID-1
1950
SwissProt-1
P01133
Organism-2
Mouse
基因ID-2
13645
SwissProt-2
P01132
背景
This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],
细胞定位
Membrane; Single-pass type I membrane protein.
