- 产品信息
商品描述
靶点-Target
ASIC1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,IHC-f,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70-75kD
推荐稀释比
WB 1:500-2000;IHC 1:500-200;ELISA 1:10000-20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic peptide from human protein at AA range: 220-280
特异性
The antibody detects endogenous ASIC1
基因名称
ASIC1 ACCN2 BNAC2
蛋白名称
Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)
别名
Acid-sensing ion channel 1;ASIC1;Amiloride-sensitive cation channel 2, neuronal;Brain sodium channel 2;BNaC2;
Organism-1
Human
基因ID-1
41
SwissProt-1
P78348
Organism-2
Mouse
基因ID-2
11419
SwissProt-2
Q6NXK8
Organism-3
Rat
SwissProt-3
P55926
背景
This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012],
细胞定位
Cell membrane ; Multi-pass membrane protein . Localizes in synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity). .





