FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DCT
反应性
Human,Mouse(93%),
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
59kD
推荐稀释比
WB 1:500-2000;ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic peptide from human protein at AA range: 171-244
特异性
The antibody detects endogenous DCT
基因名称
DCT TYRP2
蛋白名称
DCT
别名
L-dopachrome tautomerase;DCT;DT;L-dopachrome Delta-isomerase;Tyrosinase-related protein 2;TRP-2;TRP2;
Organism-1
Human
基因ID-1
1638
SwissProt-1
P40126
Organism-2
Mouse
基因ID-2
13190
SwissProt-2
P29812
背景
catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.,
细胞定位
Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. .
