Histone H2A.Z Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617552

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商品描述
  • 靶点-Target

    Histone H2A.Z

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    20kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:10000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthetic peptide from human protein at AA range: 1-30

  • 特异性

    The antibody detects endogenous Histone H2A.Z

  • 基因名称

    H2AFZ H2AZ

  • 蛋白名称

    Histone H2A.Z (H2A/z)

  • 别名

    Histone H2A.Z;H2A/z;

  • Organism-1

    Human

  • 基因ID-1

    3015

  • SwissProt-1

    P0C0S5

  • Organism-2

    Mouse

  • 基因ID-2

    51788

  • SwissProt-2

    P0C0S6

  • Organism-3

    Rat

  • SwissProt-3

    P0C0S7

  • 背景

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus. Chromosome.