FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
WISP-3
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-2000;ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human WISP3. AA range:1-50
特异性
The antibody detects endogenous WISP-3
基因名称
WISP3 CCN6 UNQ462/PRO790/PRO956
蛋白名称
WNT1-inducible-signaling pathway protein 3 (WISP-3) (CCN family member 6)
别名
WNT1-inducible-signaling pathway protein 3;WISP-3;CCN family member 6;
Organism-1
Human
基因ID-1
8838
SwissProt-1
O95389
Organism-2
Mouse
基因ID-2
327743
SwissProt-2
D3Z5L9
背景
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple
细胞定位
Secreted . Mitochondrion . Associated with membranes. .
