FAM48A Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617539

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商品描述
  • 靶点-Target

    FAM48A

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    85kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:10000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A. AA range:231-280

  • 特异性

    The antibody detects endogenous FAM48A protein

  • 基因名称

    FAM48A C13orf19 FP757

  • 蛋白名称

    family with sequence similarity 48, member A

  • 别名

    FAM48A C13orf19 FP757

  • Organism-1

    Human

  • 基因ID-1

    55578

  • SwissProt-1

    Q8NEM7

  • Organism-2

    Mouse

  • 基因ID-2

    56790

  • SwissProt-2

    Q7TT00

  • Organism-3

    Rat

  • SwissProt-3

    Q66HC7

  • 背景

    function:Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail.,similarity:Belongs to the FAM48 family.,subunit:Interacts with MAPK14.,tissue specificity:Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.,

  • 细胞定位

    Nucleus .