FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MIB1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
130kD
推荐稀释比
IHC: 100-300;WB 1:500-2000;ELISA 1:10000-20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthetic peptide from human protein at AA range: 901-950
特异性
The antibody detects endogenous MIB1 protein
基因名称
MIB1 DIP1 KIAA1323 ZZANK2
蛋白名称
mindbomb homolog 1 (Drosophila)
别名
MIB1 DIP1 KIAA1323 ZZANK2
Organism-1
Human
基因ID-1
57534
SwissProt-1
Q86YT6
Organism-2
Mouse
基因ID-2
225164
SwissProt-2
Q80SY4
背景
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013],
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Cell membrane . Localizes to the plasma membrane (By similarity). According to PubMed:15048887, it is mitochondrial, however such localization remains unclear. Displaced from centriolar satellites in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock. .
