Factor IX Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617521

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商品描述
  • 靶点-Target

    Factor IX

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    52kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:10000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from Factor IX at AA range: 412-461

  • 特异性

    Factor IX Polyclonal Antibody detects endogenous levels of Factor IX

  • 基因名称

    F9 Factor IX

  • 蛋白名称

    Factor IX

  • 别名

    Coagulation factor IX;Christmas factor;Plasma thromboplastin component;PTC;[Cleaved into: Coagulation factor IXa light chain;Coagulation factor IXa heavy chain]

  • Organism-1

    Human

  • 基因ID-1

    2158

  • SwissProt-1

    P00740

  • Organism-2

    Mouse

  • 基因ID-2

    14071

  • SwissProt-2

    P16294

  • Organism-3

    Rat

  • SwissProt-3

    P16296

  • 背景

    This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015],

  • 细胞定位

    Secreted .