Plasminogen receptor Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617517
- 产品信息
商品描述
靶点-Target
Plasminogen receptor
反应性
Human,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
17kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human PLGRKT. AA range:1-50
特异性
Plasminogen receptor Polyclonal Antibody detects endogenous levels of Plasminogen receptor
基因名称
PLGRKT
蛋白名称
Plasminogen receptor
别名
Plasminogen receptor;KT;Plg-R;KT;
Organism-1
Human
基因ID-1
55848
SwissProt-1
Q9HBL7
Organism-2
Mouse
基因ID-2
67759
SwissProt-2
Q9D3P8
Organism-3
Rat
SwissProt-3
D4ACN8
背景
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.
细胞定位
Cell membrane ; Multi-pass membrane protein . Colocalizes on the cell surface with urokinase plasminogen activator surface receptor/PLAUR. .





