Plasminogen receptor Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617517

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商品描述
  • 靶点-Target

    Plasminogen receptor

  • 反应性

    Human,Rat

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    17kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human PLGRKT. AA range:1-50

  • 特异性

    Plasminogen receptor Polyclonal Antibody detects endogenous levels of Plasminogen receptor

  • 基因名称

    PLGRKT

  • 蛋白名称

    Plasminogen receptor

  • 别名

    Plasminogen receptor;KT;Plg-R;KT;

  • Organism-1

    Human

  • 基因ID-1

    55848

  • SwissProt-1

    Q9HBL7

  • Organism-2

    Mouse

  • 基因ID-2

    67759

  • SwissProt-2

    Q9D3P8

  • Organism-3

    Rat

  • SwissProt-3

    D4ACN8

  • 背景

    Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein . Colocalizes on the cell surface with urokinase plasminogen activator surface receptor/PLAUR. .