- 产品信息
商品描述
靶点-Target
C8 β
反应性
Human,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-2000;ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human C8B. AA range:371-420
特异性
C8 β Polyclonal Antibody detects endogenous levels of C8 β
基因名称
C8B
蛋白名称
C8 β
别名
Complement component C8 beta chain;Complement component 8 subunit beta;
Organism-1
Human
基因ID-1
732
SwissProt-1
P07358
Organism-2
Mouse
基因ID-2
110382
SwissProt-2
Q8BH35
Organism-3
Rat
SwissProt-3
P55314
背景
This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
细胞定位
Secreted.





