C8 β Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617516

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商品描述
  • 靶点-Target

    C8 β

  • 反应性

    Human,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    70kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:10000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human C8B. AA range:371-420

  • 特异性

    C8 β Polyclonal Antibody detects endogenous levels of C8 β

  • 基因名称

    C8B

  • 蛋白名称

    C8 β

  • 别名

    Complement component C8 beta chain;Complement component 8 subunit beta;

  • Organism-1

    Human

  • 基因ID-1

    732

  • SwissProt-1

    P07358

  • Organism-2

    Mouse

  • 基因ID-2

    110382

  • SwissProt-2

    Q8BH35

  • Organism-3

    Rat

  • SwissProt-3

    P55314

  • 背景

    This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],

  • 细胞定位

    Secreted.