- 产品信息
商品描述
靶点-Target
TyrRS
反应性
Human,Mouse,Rat
应用
WB,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:10000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human YARS. AA range:451-500
特异性
TyrRS Polyclonal Antibody detects endogenous levels of TyrRS
基因名称
YARS
蛋白名称
TyrRS
别名
Tyrosine--tRNA ligase, cytoplasmic;Tyrosyl-tRNA synthetase;TyrRS;
Organism-1
Human
基因ID-1
8565
SwissProt-1
P54577
Organism-2
Mouse
基因ID-2
107271
SwissProt-2
Q91WQ3
Organism-3
Rat
SwissProt-3
Q4KM49
背景
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm .





