- 产品信息
商品描述
靶点-Target
PTH-rP
反应性
Human,Rat,Mouse,
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
25kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human PTHLH. AA range:101-150
特异性
PTH-rP Polyclonal Antibody detects endogenous levels of PTH-rP
基因名称
PTHLH
蛋白名称
PTH-rP
别名
Parathyroid hormone-related protein;PTH-rP;PTHrP;Parathyroid hormone-like protein;PLP;[Cleaved into: PTHrP[1-36];PTHrP[38-94];Osteostatin;PTHrP[107-139];]
Organism-1
Human
基因ID-1
5744
SwissProt-1
P12272
Organism-2
Mouse
SwissProt-2
P22858
背景
parathyroid hormone like hormone(PTHLH) Homo sapiens The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. [provided by RefSeq, Nov 2013],
细胞定位
Cytoplasm. Nucleus. Secreted.





