FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ETBR
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
IHC: 100-300;WB 1:500-2000;ELISA 1:10000-20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from ETBR at AA range: 31-80
特异性
ETBR Polyclonal Antibody detects endogenous levels of ETBR
基因名称
EDNRB
蛋白名称
ETBR
别名
Endothelin B receptor;ET-B;ET-BR;Endothelin receptor non-selective type;
Organism-1
Human
基因ID-1
1910
SwissProt-1
P24530
Organism-2
Mouse
基因ID-2
13618
SwissProt-2
P48302
背景
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],
细胞定位
Cell membrane ; Multi-pass membrane protein. internalized after activation by endothelins. .
