Collagen I Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617496
- 产品信息
商品描述
靶点-Target
Collagen I
反应性
Human,Mouse,Rat
应用
WB IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
135kD
推荐稀释比
WB 1:500-2000;IF 1:100-300;ELISA 1:5000-20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Collagen I . at AA range: 1200-1217
特异性
Collagen I Polyclonal Antibody detects endogenous levels of Collagen I
蛋白名称
Collagen I
别名
collagen, type I, alpha 2
Organism-1
Human
基因ID-1
1277;1278
SwissProt-1
P08123;P02452
背景
This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008],
细胞定位
Secreted, extracellular space, extracellular matrix .





