E-Selectin Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617478

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商品描述
  • 靶点-Target

    E-Selectin

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    66kD

  • 推荐稀释比

    IHC: 100-300;WB 1:500-2000;ELISA 1:10000-20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELE. AA range:100-150

  • 特异性

    E-Selectin Polyclonal Antibody detects endogenous levels of E-Selectin

  • 基因名称

    SELE ELAM1

  • 蛋白名称

    E-Selectin

  • 别名

    selectin E

  • Organism-1

    Human

  • 基因ID-1

    6401

  • SwissProt-1

    P16581

  • Organism-2

    Mouse

  • 基因ID-2

    20339

  • SwissProt-2

    Q00690

  • 背景

    The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane ; Single-pass type I membrane protein.