FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
K-Ras
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
IHC: 100-300;WB 1:500-1:2000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human KRAS. AA range:150-189
特异性
K-Ras Polyclonal Antibody detects endogenous levels of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
基因名称
KRAS
蛋白名称
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
别名
GTPase KRas;K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras;[Cleaved into: GTPase KRas, N-terminally processed]
Organism-1
Human
基因ID-1
3845
SwissProt-1
P01116
Organism-2
Mouse
基因ID-2
16653
SwissProt-2
P32883
Organism-3
Rat
SwissProt-3
P08644
背景
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Endomembrane system . Cytoplasm, cytosol .; [Isoform 2B]: Cell membrane ; Lipid-anchor .
