- 产品信息
商品描述
靶点-Target
CD158e
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Killer cell immunoglobulin-like receptor 3DL1 at AA range: 21-70
特异性
CD158e Polyclonal Antibody detects endogenous levels of CD158e protein.
基因名称
KIR3DL1
蛋白名称
Killer cell immunoglobulin-like receptor 3DL1
别名
KIR3DL1;CD158E;NKAT3;NKB1;Killer cell immunoglobulin-like receptor 3DL1;CD158 antigen-like family member E;HLA-BW4-specific inhibitory NK cell receptor;MHC class I NK cell receptor;Natural killer-associated transcript 3;NKAT-3;p70 natural killer cell receptor clones CL-2/CL-11;p70 NK receptor CL-2/CL-11;CD158e
Organism-1
Human
基因ID-1
3811
SwissProt-1
P43629
Organism-2
Mouse
SwissProt-2
P83555
Organism-3
Rat
基因ID-3
353253
SwissProt-3
P83556
背景
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1(KIR3DL1) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the
细胞定位
Cell membrane; Single-pass type I membrane protein.





