- 产品信息
商品描述
靶点-Target
Dectin-2
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
23kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human Dectin-2.
特异性
Dectin-2 Polyclonal Antibody detects endogenous levels of Dectin-2 protein.
基因名称
CLEC6A
蛋白名称
C-type lectin domain family 6 member A
别名
CLEC6A;CLECSF10;DECTIN2;C-type lectin domain family 6 member A;C-type lectin superfamily member 10;Dendritic cell-associated C-type lectin 2;DC-associated C-type lectin 2;Dectin-2
Organism-1
Human
基因ID-1
93978
SwissProt-1
Q6EIG7
Organism-2
Mouse
SwissProt-2
Q9JKF4
背景
The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
细胞定位
Cell membrane ; Single-pass type II membrane protein .





