Dectin-2 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617432

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商品描述
  • 靶点-Target

    Dectin-2

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    23kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from the Internal region of human Dectin-2.

  • 特异性

    Dectin-2 Polyclonal Antibody detects endogenous levels of Dectin-2 protein.

  • 基因名称

    CLEC6A

  • 蛋白名称

    C-type lectin domain family 6 member A

  • 别名

    CLEC6A;CLECSF10;DECTIN2;C-type lectin domain family 6 member A;C-type lectin superfamily member 10;Dendritic cell-associated C-type lectin 2;DC-associated C-type lectin 2;Dectin-2

  • Organism-1

    Human

  • 基因ID-1

    93978

  • SwissProt-1

    Q6EIG7

  • Organism-2

    Mouse

  • SwissProt-2

    Q9JKF4

  • 背景

    The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],

  • 细胞定位

    Cell membrane ; Single-pass type II membrane protein .