- 产品信息
商品描述
靶点-Target
IRF-1
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human IRF1. AA range:91-140
特异性
IRF-1 Polyclonal Antibody detects endogenous levels of IRF-1 protein.
基因名称
IRF1
蛋白名称
Interferon regulatory factor 1
别名
IRF1;Interferon regulatory factor 1;IRF-1
Organism-1
Human
基因ID-1
3659
SwissProt-1
P10914
Organism-2
Mouse
基因ID-2
16362
SwissProt-2
P15314
Organism-3
Rat
基因ID-3
24508
SwissProt-3
P23570
背景
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . MYD88-associated IRF1 migrates into the nucleus more efficiently than non-MYD88-associated IRF1. .





