FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BMP-6
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human BMP6. AA range:341-390
特异性
BMP-6 Polyclonal Antibody detects endogenous levels of BMP-6 protein.
基因名称
BMP6
蛋白名称
Bone morphogenetic protein 6
别名
BMP6;VGR;Bone morphogenetic protein 6;BMP-6;VG-1-related protein;VG-1-R;VGR-1
Organism-1
Human
基因ID-1
654
SwissProt-1
P22004
Organism-2
Mouse
基因ID-2
12161
SwissProt-2
P20722
Organism-3
Rat
基因ID-3
25644
SwissProt-3
Q04906
背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016],
细胞定位
Secreted .
