- 产品信息
商品描述
靶点-Target
GDF-6
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human GDF6. AA range:311-360
特异性
GDF-6 Polyclonal Antibody detects endogenous levels of GDF-6 protein.
基因名称
GDF6
蛋白名称
Growth/differentiation factor 6
别名
GDF6;GDF16;Growth/differentiation factor 6;GDF-6;Growth/differentiation factor 16
Organism-1
Human
基因ID-1
392255
SwissProt-1
Q6KF10
Organism-2
Mouse
基因ID-2
242316
SwissProt-2
P43028
Organism-3
Rat
基因ID-3
252834
SwissProt-3
Q6HA10
背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016],
细胞定位
Secreted .





