- 产品信息
商品描述
靶点-Target
Lefty
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human LEFTY1/LEFTY2. AA range:301-350
特异性
Lefty Polyclonal Antibody detects endogenous levels of Lefty protein.
基因名称
LEFTY1/LEFTY2
蛋白名称
Left-right determination factor 1/Left-right determination factor 2
别名
LEFTY1;LEFTB;LEFTYB;Left-right determination factor 1;Left-right determination factor B;Protein lefty-1;Protein lefty-B;LEFTY2;EBAF;LEFTA;LEFTYA;TGFB4;PSEC0024;Left-right determination factor 2;Endometrial bleeding-associated factor;Left-right determination factor A;Protein lefty-2;Protein lefty-A;Transforming growth factor beta-4;TGF-beta-4
Organism-1
Human
基因ID-1
10637;7044
SwissProt-1
O75610;O00292
Organism-2
Mouse
基因ID-2
13590;320202
背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Aug 2016],
细胞定位
Secreted.





