- 产品信息
商品描述
靶点-Target
GDF-3
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
41kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360
特异性
GDF-3 Polyclonal Antibody detects endogenous levels of GDF-3 protein.
基因名称
GDF3
蛋白名称
Growth/differentiation factor 3
别名
GDF3;Growth/differentiation factor 3;GDF-3
Organism-1
Human
基因ID-1
9573
SwissProt-1
Q9NR23
Organism-2
Mouse
基因ID-2
14562
SwissProt-2
Q07104
背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],
细胞定位
Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. .





