Amphiregulin Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

一键复制产品信息
产品规格:
  • 50μL
  • 100μL
货号:

FAB2617393

  • 产品信息
  • 注意事项
  • 实验验证
  • 产品声明
  • 引用文献
  • 相关产品
  • 文件下载
商品描述
  • 靶点-Target

    Amphiregulin

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    17kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human AREG/AREGB. AA range:91-140

  • 特异性

    Amphiregulin Polyclonal Antibody detects endogenous levels of Amphiregulin protein.

  • 基因名称

    AREG/AREGB

  • 蛋白名称

    Amphiregulin

  • 别名

    AREG;SDGF;AREGB;Amphiregulin;AR;Colorectum cell-derived growth factor;CRDGF

  • Organism-1

    Human

  • 基因ID-1

    374;727738

  • SwissProt-1

    P15514

  • Organism-2

    Mouse

  • 基因ID-2

    11839

  • SwissProt-2

    P31955

  • Organism-3

    Rat

  • 基因ID-3

    29183

  • SwissProt-3

    P24338

  • 背景

    The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014],

  • 细胞定位

    Membrane; Single-pass membrane protein.