Amphiregulin Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2617393
- 产品信息
商品描述
靶点-Target
Amphiregulin
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
17kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human AREG/AREGB. AA range:91-140
特异性
Amphiregulin Polyclonal Antibody detects endogenous levels of Amphiregulin protein.
基因名称
AREG/AREGB
蛋白名称
Amphiregulin
别名
AREG;SDGF;AREGB;Amphiregulin;AR;Colorectum cell-derived growth factor;CRDGF
Organism-1
Human
基因ID-1
374;727738
SwissProt-1
P15514
Organism-2
Mouse
基因ID-2
11839
SwissProt-2
P31955
Organism-3
Rat
基因ID-3
29183
SwissProt-3
P24338
背景
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014],
细胞定位
Membrane; Single-pass membrane protein.





