FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EMAP II
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
34kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human AIMP1. AA range:91-140
特异性
EMAP II Polyclonal Antibody detects endogenous levels of EMAP II protein.
基因名称
AIMP1
蛋白名称
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1
别名
AIMP1;EMAP2;SCYE1;Aminoacyl tRNA synthase complex-interacting multifunctional protein 1;Multisynthase complex auxiliary component p43
Organism-1
Human
基因ID-1
9255
SwissProt-1
Q12904
Organism-2
Mouse
SwissProt-2
P31230
背景
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008],
细胞定位
Nucleus . Cytoplasm, cytosol . Secreted . Endoplasmic reticulum . Golgi apparatus . Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels (By similarity). Secreted in response to hypoxia (PubMed:10850427). Also secreted in response to both apoptotic and necrotic cell death. .
