- 产品信息
商品描述
靶点-Target
Lambda 5
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
23kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human IGLL1. AA range:151-200
特异性
Lambda 5 Polyclonal Antibody detects endogenous levels of Lambda 5 protein.
基因名称
IGLL1
蛋白名称
Immunoglobulin lambda-like polypeptide 1
别名
IGLL1;IGL1;Immunoglobulin lambda-like polypeptide 1;CD179 antigen-like family member B;Ig lambda-5;Immunoglobulin omega polypeptide;Immunoglobulin-related protein 14.1;CD179b
Organism-1
Human
基因ID-1
3543
SwissProt-1
P15814
Organism-2
Mouse
基因ID-2
16136
SwissProt-2
P20764
背景
immunoglobulin lambda like polypeptide 1(IGLL1) Homo sapiens The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum . Secreted . In pre-B cells, localizes predominantly to the endoplasmic reticulum. .





