- 产品信息
商品描述
靶点-Target
CD305
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
32kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human LAIR1. AA range:21-70
特异性
CD305 Polyclonal Antibody detects endogenous levels of CD305 protein.
基因名称
LAIR1
蛋白名称
Leukocyte-associated immunoglobulin-like receptor 1
别名
LAIR1;CD305;Leukocyte-associated immunoglobulin-like receptor 1;LAIR-1;hLAIR1;CD305
Organism-1
Human
基因ID-1
3903
SwissProt-1
Q6GTX8
Organism-2
Mouse
基因ID-2
52855
SwissProt-2
Q8BG84
Organism-3
Rat
基因ID-3
574531
SwissProt-3
P0C1X9
背景
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
细胞定位
Cell membrane ; Single-pass type I membrane protein .





