CD158a Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2617371

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商品描述
  • 靶点-Target

    CD158a

  • 反应性

    Human

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    39kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human KIR2DL1. AA range:131-180

  • 特异性

    CD158a Polyclonal Antibody detects endogenous levels of CD158a protein.

  • 基因名称

    KIR2DL1

  • 蛋白名称

    Killer cell immunoglobulin-like receptor 2DL1

  • 别名

    KIR2DL1;CD158A;NKAT1;Killer cell immunoglobulin-like receptor 2DL1;CD158 antigen-like family member A;MHC class I NK cell receptor;Natural killer-associated transcript 1;NKAT-1;p58 natural killer cell receptor clones CL-42/47.11;p58 NK receptor CL-42/47.11;p58.1 MHC class-I-specific NK receptor;CD158a

  • Organism-1

    Human

  • 基因ID-1

    3802

  • SwissProt-1

    P43626

  • 背景

    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the

  • 细胞定位

    Cell membrane ; Single-pass type I membrane protein.