- 产品信息
商品描述
靶点-Target
CD244
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD244. AA range:101-150
特异性
CD244 Polyclonal Antibody detects endogenous levels of CD244 protein.
基因名称
CD244
蛋白名称
Natural killer cell receptor 2B4
别名
CD244;2B4;Natural killer cell receptor 2B4;NK cell activation-inducing ligand;NAIL;NK cell type I receptor protein 2B4;NKR2B4;h2B4;CD244
Organism-1
Human
基因ID-1
51744
SwissProt-1
Q9BZW8
Organism-2
Mouse
SwissProt-2
Q07763
背景
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],
细胞定位
Membrane ; Single-pass type I membrane protein . Cell membrane . Receptor engagement results in a recruitment to lipid drafts essential for the subsequent tyrosine phosphorylation of the ITSMs. .





